Seminal Contributions to Dialysis Daily - dialysis programme : indications and results *

(i) Routine biochemistry: Plasma BUN, creatinine, electroThis paper deals with the results of clinical and laboratlytes, haematocrit, etc. ory investigations carried out on six chronic uraemic (ii) Erythropoiesis studies: 59Fe, 51Cr, transferrin, reticulopatients who had been on RDT for 1–3 years. They cytes, sternal puncture. presented evidence of dialysis resistant signs and (iii) Blood pressure studies: Plasma renin concentration, symptoms despite an increase in the total hours of serum aldosterone, 22 Na, cardiac index. dialysis/week from 22 to 30. These patients were put (iv) Nerve conduction velocity: peroneal and median nerves. on a new dialysis programme with short daily dialyses (v) Iliac crest percutaneous bone biopsies: using a trephine (3–4 h) for 5 days/week. of 5 mm internal diameter; calcium balance and 47Ca The overall results of this study indicate that a daily turnover. (vi) Metabolic studies: glucose (peripheral uptake, oral tolerdialysis programme may be considered as the most ance curves); lipid (triglycerides, NEFA, phospholipid physiological approach to dialysis treatment yielding and cholesterol ); serum aminoacids. Computer recordthe best clinical results. ing of all dialysis data was used. Results were recorded, memorized and then processed by punch cards.